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Genomic variations associated with risk and protection against vincristine-induced peripheral neuropathy in pediatric cancer patients

Abstract Vincristine-induced peripheral neuropathy is a common and highly debilitating toxicity from vincristine treatment that affects quality of life and often requires dose reduction, potentially affecting survival. Although previous studies demonstrated genetic factors are associated with vincri...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kheireddin Mufti, Miguel Cordova, Erika N. Scott, Jessica N. Trueman, Jessica M. Lovnicki, Catrina M. Loucks, Shahrad R. Rassekh, Colin J. D. Ross, Bruce C. Carleton, On behalf of the Canadian Pharmacogenomics Network for Drug Safety Consortium
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2024-11-01
Rangatū:npj Genomic Medicine
Urunga tuihono:https://doi.org/10.1038/s41525-024-00443-7
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