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Arginine Methyltransferases as Regulators of RNA-Binding Protein Activities in Pathogenic Kinetoplastids

A large number of eukaryotic proteins are processed by single or combinatorial post-translational covalent modifications that may alter their activity, interactions and fate. The set of modifications of each protein may be considered a “regulatory code”. Among the PTMs, arginine methylation, catalyz...

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Main Authors: Gustavo D. Campagnaro, Edward Nay, Michael J. Plevin, Angela K. Cruz, Pegine B. Walrad
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
arginine methylation
PRMT
RNA-binding protein
Trypanosoma
Leishmania
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.692668/full
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