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Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.

PABPC1 (cytosolic poly(A)-binding protein 1) is an RNA-binding protein that binds to the poly(A) tail of mRNAs to promote translation and mRNA turnover. In addition to RNA-binding domains, PABPC1 contains a unique protein-protein interaction domain, MLLE (also known as PABC) that binds regulatory pr...

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Autori principali: Guennadi Kozlov, Kalle Gehring
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-04-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2854688?pdf=render
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