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Increased Tumor Necrosis Factor Superfamily Members in Neuroinflammatory Schizophrenia and Bipolar Disorder Midbrains

Background: Neuroinflammation is a key neuropathological finding in schizophrenia and bipolar disorder, as increased cytokines are found in the midbrain of these individuals. However, the most upregulated inflammatory cytokines and most activated downstream signaling pathway(s) are unidentified. Met...

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Principais autores: Gerardo Mendez-Victoriano, Yunting Zhu, Layla Neuhaus, Suhaana Shaik, Frank Middleton, Yuji Kondo, Amir Fayyazuddin, Daniel Hoeppner, Sofía Puvogel, Astrid Alsema, Laura Kracht, Mitsuyuki Matsumoto, Bart J.L. Eggen, Adam K. Walker, Maree J. Webster, Iris E.C. Sommer, Cynthia S. Weickert
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-03-01
Serier:Biological Psychiatry Global Open Science
Fag:
Bipolar disorder
Midbrain
mRNA
RNA-seq
Schizophrenia
TNFSF
Online adgang:http://www.sciencedirect.com/science/article/pii/S2667174325002046
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