Early prediction of pathologic complete response to neoadjuvant chemotherapy based on longitudinal total choline of MR spectroscopy in patients with breast cancer

Abstract Background Accurately predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) early during treatment could enable therapy adaptation. Total choline (tCho) measured by Proton MR spectroscopy (1H-MRS) reflects tumor metabolism and may serve as an early biomarker, but...

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Detalhes bibliográficos

Principais autores:	Shuling Liu, Xiaoxia Wang, Fujie Jiang, Sun Tang, Ying Cao, Lu Wang, Huifang Chen, Xiangfei Zeng, Yao Huang, Lan Li, Renzhi Zhang, Jiuquan Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	BMC Medical Imaging
Assuntos:	Breast cancer Neoadjuvant chemotherapy Pathologic complete response Proton MR spectroscopy Choline
Acesso em linha:	https://doi.org/10.1186/s12880-026-02160-2
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