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LT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunity.

Currently, there is a shortage of adjuvants that can be employed with protein subunit vaccines to enhance protection against biological threats. LT-IIb(T13I) is an engineered nontoxic derivative of LT-IIb, a member of the type II subfamily of heat labile enterotoxins expressed by Escherichia coli, t...

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Váldodahkkit: Christopher J Greene, Chrystal M Chadwick, Lorrie M Mandell, John C Hu, Joanne M O'Hara, Robert N Brey, Nicholas J Mantis, Terry D Connell
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2013-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3732243?pdf=render
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