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Screening and construction of nanobodies against human CD93 using phage libraries and study of their antiangiogenic effects

BackgroundCluster of Differentiation 93 (CD93) plays an important role in angiogenesis and is considered an important target for inhibiting tumor angiogenesis, but there are currently no therapeutic antibodies against CD93 in the clinic. Thus, we describe the screening of novel nanobodies (Nbs) targ...

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Hauptverfasser: Hui Miao, Yiling Wu, Hao Ouyang, Peiwen Zhang, Wenyun Zheng, Xingyuan Ma
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-05-01
Schriftenreihe:Frontiers in Bioengineering and Biotechnology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1372245/full
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