Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibodyResearch in context

Summary: Background: The human respiratory syncytial virus (hRSV) is a pathogen of global concern, causing significant morbidity and mortality, mainly in preterm infants. To date, all licenced monoclonal antibodies (mAbs) developed against hRSV have targeted its surface fusion or pre-fusion protein...

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Autors principals:	Mónica A. Farías, Catalina A. Andrade, Ricardo A. Loaiza, Linmar Rodríguez-Guilarte, José T. Muñoz, Patricia Pereira-Sánchez, Natalia Muñoz-Durango, Magdalena S. Pizarro-Ortega, Benjamín Diethelm-Varela, Alejandra Pereira-Serrano, Robinson A. Ramírez, José L. Chávez, Karen Bohmwald, Jorge A. Soto, Pablo A. González, Susan M. Bueno, Alexis M. Kalergis
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-01-01
Col·lecció:	EBioMedicine
Matèries:	Human respiratory syncytial virus Nucleoprotein Monoclonal antibodies Antibody-dependent cellular cytotoxicity Complement-dependent cytotoxicity
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2352396425005547
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