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Coordination of Bactericidal and Iron Regulatory Functions of Hepcidin in Innate Antimicrobial Immunity in a Zebrafish Model

Abstract Hepcidin acts as both an antimicrobial peptide and a hormonal regulator of iron homeostasis; however, the biological significance of this dual-function in immune reactions remains elusive. In this study, we provide experimental evidence regarding the coordination of this dual-function in th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Xiao-feng Jiang, Zhi-fei Liu, Ai-fu Lin, Li-xin Xiang, Jian-zhong Shao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2017-06-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-017-04069-x
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