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Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22

Abstract Background The human genome contains remnants of ancient retroviral infections called human endogenous retroviruses (HERV). Their expression is often observed in several diseases of autoimmune or inflammatory nature. However, the exact biological mechanisms induced by HERVs are still poorly...

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Päätekijät: Arttu Autio, Tapio Nevalainen, Binisha H. Mishra, Marja Jylhä, Heini Flinck, Mikko Hurme
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2020-05-01
Sarja:Immunity & Ageing
Aiheet:
Human endogenous retrovirus
HERV-K (HML-2)
ERVK-7
Immunosenescence
GSEA
Next-generation sequencing
Linkit:http://link.springer.com/article/10.1186/s12979-020-00182-0
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