Kazachstania pintolopesii triggers an immune-endothelial-fibroblast cascade and drives inflammatory arthritis and tissue fibrosis in genetically susceptible hosts

Emerging evidence underscores the critical role of microbiota dysbiosis in autoimmune pathogenesis, yet direct links between specific microbial species and disease mechanisms remain poorly defined. Our prior work identified Kazachstania pintolopesii, a gut-dwelling fungus isolated from spontaneous a...

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Principais autores:	Haiting Zhang, Lei Li, Duanling Tan, Chulan Lin, Yanqing Zhang, Diling Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-12-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	autoimmunity inflammatory arthritis Kazachstania pintolopesii multicellular crosstalk tissue fibrosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1738184/full
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