Machine learning unveils an immune-related DNA methylation profile in germline DNA from breast cancer patients

Abstract Background There is an unmet need for precise biomarkers for early non-invasive breast cancer detection. Here, we aimed to identify blood-based DNA methylation biomarkers that are associated with breast cancer. Methods DNA methylation profiling was performed for 524 Asian Chinese individual...

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Autores principales:	Ning Yuan Lee, Melissa Hum, Guek Peng Tan, Ai Choo Seah, Pei-Yi Ong, Patricia T. Kin, Chia Wei Lim, Jens Samol, Ngiap Chuan Tan, Hai-Yang Law, Min-Han Tan, Soo-Chin Lee, Peter Ang, Ann S. G. Lee
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-05-01
Colección:	Clinical Epigenetics
Materias:	Breast cancer DNA methylation Peripheral blood Early detection Liquid biopsy Biomarker
Acceso en línea:	https://doi.org/10.1186/s13148-024-01674-2
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