Intratumoral PD1⁺CD38⁺Tim3⁺ CD8⁺ T Cells in Pre-BCG Tumor Tissues Are Associated with Poor Responsiveness to BCG Immunotherapy in Patients with Non-Muscle Invasive Bladder Cancer

Intravesical immunotherapy with Bacillus Calmette–Guerin (BCG) is a standard of care therapy for non-muscle invasive bladder cancer (NMIBC), which accounts for about 75% of newly diagnosed urothelial cancer. However, given the frequent recurrence and progression, identification of a pre-treatment bi...

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Autori principali:	Debashree Basak, Soumya Mondal, Swadeep Kumar Srivastava, Deborpita Sarkar, Ishita Sarkar, Sukanya Basu, Arpita Bhoumik, Snehanshu Chowdhury, Dilip Kumar Pal, Shilpak Chatterjee
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2023-07-01
Serie:	Cells
Soggetti:	non-muscle invasive bladder cancer BCG immunotherapy CD8<sup>+</sup> T cells biomarker prognosis
Accesso online:	https://www.mdpi.com/2073-4409/12/15/1939
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