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Identification of Acid Hydrolysis Metabolites of the Pimelea Toxin Simplexin for Targeted UPLC-MS/MS Analysis

Pimelea poisoning of cattle is a unique Australian toxic condition caused by the daphnane orthoester simplexin present in native Pimelea pasture plants. Rumen microorganisms have been proposed to metabolise simplexin by enzymatic reactions, likely at the orthoester and epoxide moieties of simplexin,...

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Principais autores: Zhi Hung Loh, Natasha L. Hungerford, Diane Ouwerkerk, Athol V. Klieve, Mary T. Fletcher
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-09-01
Serier:Toxins
Fag:
Pimelea
simplexin
plant toxin
mass spectrometry
metabolite
rumen
Online adgang:https://www.mdpi.com/2072-6651/15/9/551
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