Effects of pomegranate seed extract and ellagic acid on miR-16-5p and miR-34a-5p expression, cell cycle, and apoptosis in MCF-7 cells

Background and purpose: The expression of Homo sapiens (has)-miR-16-5p and hsa-miR-34a-5p with anti-tumor effects is downregulated in cancer cells. To maintain these gene expressions in cancer cells, we evaluated the effects of pomegranate seed extract (PSE) and ellagic acid (EA) on hsa-miR-16-5p an...

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Detalhes bibliográficos

Principais autores:	Zahra Sadeghi, Mohammadreza Sharifi, Mehrnoush Malekzadeh, Sho’leh Ghaedamini, Batool Hashemibeni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2026-05-01
coleção:	Research in Pharmaceutical Sciences
Assuntos:	breast cancer ellagic acid hsa-mir-16-5p hsa-mir-34a-5p pomegranate seed extract.
Acesso em linha:	https://journals.lww.com/10.4103/RPS.RPS_247_24
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