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STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors.

Signal transducer and activator of transcription-3 (STAT3) is an oncogenic transcription factor implicated in carcinogenesis, tumor progression, and drug resistance in head and neck squamous cell carcinoma (HNSCC). A decoy oligonucleotide targeting STAT3 offers a promising anti-tumor strategy, but a...

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Principais autores: Thiruganesh Ramasamy, Xucai Chen, Bin Qin, Daniel E Johnson, Jennifer R Grandis, Flordeliza S Villanueva
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2020-01-01
סדרה:PLoS ONE
גישה מקוונת:https://doi.org/10.1371/journal.pone.0242264
תגים: הוספת תג
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