LGR5 expression and clinicopathological features of the invasive front in the fat infiltration area of pancreatic cancer

Abstract Background Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a strong cancer stem cell marker in colorectal cancer; however, there are many unclear aspects of LGR5 expression in pancreatic cancer. It has been reported that the interaction between tumor cells and stroma a...

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Hlavní autoři:	Masato Kamakura, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Yasuhiro Kinugawa, Tadanobu Nagaya, Takahiro Yoshizawa, Akira Shimizu, Hiroyoshi Ota, Takeji Umemura
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2022-02-01
Edice:	Diagnostic Pathology
Témata:	Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) RNA in situ hybridization Pancreatic ductal adenocarcinoma cancer stem cell Fat invasion
On-line přístup:	https://doi.org/10.1186/s13000-022-01203-w
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