Finerenone attenuates chronic fibrotic remodeling during the AKI-CKD transition in an ischemia-reperfusion-induced acute kidney injury mouse model

Objective: The transition from acute kidney injury (AKI) to chronic kidney disease (CKD) is a major cause of poor prognosis in renal injury, and preventing the progression from AKI to CKD has important clinical significance. Finerenone exerts renoprotective effects, however, its role in the AKI-CKD...

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Hauptverfasser:	Ruoshan Lian, Siyi Rao, Zongli Zheng, Sha Tang, Jianxin Wan, Yi Chen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2026-12-01
Schriftenreihe:	Renal Failure
Schlagworte:	Acute kidney injury (AKI) chronic kidney disease (CKD) podocyte finerenone (fin) mineralocorticoid receptor (MR)
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/0886022X.2026.2691338
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