Impact of HPV vaccine on CIN2+ recurrence after conization: a systematic review and meta-analysis of vaccination timing, valency and surgical margins

BackgroundProphylactic Human Papillomavirus (HPV) vaccines prevent high-grade cervical lesions, but their role as adjuvant therapy after conization for high-grade cervical intraepithelial neoplasia (CIN2+) remains uncertain, particularly regarding vaccine type, timing, and margin status. This review...

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Xehetasun bibliografikoak

Egile Nagusiak:	Mauro Francesco Pio Maiorano, Ambrogio Cazzolla, Brigida Anna Maiorano, Vera Loizzi, Gennaro Cormio, Giuseppe Colonna, Salvatore Lopez
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2026-02-01
Saila:	Frontiers in Oncology
Gaiak:	cervical cancer conization Gardasil vaccine HPV vaccine HPV vaccine after conization HPV vaccine CIN HPV vaccine conization systematic review
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1748972/full
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