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Feasibility of quantifying SDC2 methylation in stool DNA for early detection of colorectal cancer

Abstract Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected genes and early during CRC development, which has emerged as a new epigenetic biomarker for early detection of CRC...

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Principais autores: Tae Jeong Oh, Hyun Il Oh, Yang Yei Seo, Dongjun Jeong, Changjin Kim, Hyoun Woo Kang, Yoon Dae Han, Hyun Cheol Chung, Nam Kyu Kim, Sungwhan An
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-12-01
coleção:Clinical Epigenetics
Assuntos:
Colorectal cancer
Early detection
Methylation
Precancerous lesion
SDC2
Stool DNA
Acesso em linha:http://link.springer.com/article/10.1186/s13148-017-0426-3
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