Dopaminergic neuronal differentiation from the forebrain-derived human neural stem cells induced in cultures by using a combination of BMP-7 and pramipexole with growth factors

Transplantation of dopaminergic (DA) neurons is considered to be the most promising therapeutic strategy for replacing degenerated dopamine cells in the midbrain of Parkinson’s disease (PD), thereby restoring normal neural circuit function and slow clinical progression of the disease. Human neural s...

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Autors principals:	Hongna eYang, Jing eWang, Feng eWang, Xiaodun eLiu, Heng eChen, WeiMing eDuan, Tingyu eQu
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2016-04-01
Col·lecció:	Frontiers in Neural Circuits
Matèries:	Th Dopamine release BMP-7 PRX dopamiergic neurons forebrain-derived neural stem cells
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fncir.2016.00029/full
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