Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy?

α-Synucleinopathies are spreading neurodegenerative disorders characterized by the intracellular accumulation of insoluble aggregates populated by α-Synuclein (α-Syn) fibrils. In Parkinson’s disease (PD) and dementia with Lewy bodies, intraneuronal α-Syn aggregates are referred to as Lewy bodies in...

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Hlavní autoři:	Francesco De Nuccio, Marianna Kashyrina, Francesca Serinelli, Florent Laferrière, Dario Domenico Lofrumento, Francesca De Giorgi, François Ichas
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-02-01
Edice:	Biomolecules
Témata:	α-Synuclein PFFs seeding spread anterior commissure Lewy neurite
On-line přístup:	https://www.mdpi.com/2218-273X/13/2/269
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