Clinically relevant benzoxaboroles inhibit mRNA processing in Trypanosoma brucei
Abstract Objective The cleavage and polyadenylation endonuclease CPSF73 is thought to be the target of the anti-trypanosomal benzoxaboroles AN7973, acoziborole and AN11736. We previously showed that AN7973 inhibits mRNA processing. We here investigated whether the drug candidates acoziborole (for hu...
-д хадгалсан:
| Үндсэн зохиолчид: | , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
BMC
2022-12-01
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| Цуврал: | BMC Research Notes |
| Нөхцлүүд: | |
| Онлайн хандалт: | https://doi.org/10.1186/s13104-022-06258-y |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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