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Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5

Cytochrome P450 gene expression is altered by various chemical compounds. In this study, we used nuclear factor erythroid 2-related factor 2 (Nrf2)–deficient (Nrf2−⧸−) mice to investigate the involvement of Nrf2 in Cyp2b10 and Cyp2a5 gene expression. Phorone, an Nrf2 activator, strongly increased Cy...

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Autori principali: Takashi Ashino, Haruyo Ohkubo-Morita, Masayuki Yamamoto, Takemi Yoshida, Satoshi Numazawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014-01-01
Serie:Redox Biology
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2213231714000081
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