Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers

Abstract Background DNA hypermethylation is an epigenetic feature that modulates gene expression, and its deregulation is observed in cancer. Previously, we identified a neural-related DNA hypermethylation fingerprint in colon cancer, where most of the top hypermethylated and downregulated genes hav...

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Auteurs principaux:	Musa Idris, Louis Coussement, Maria M. Alves, Tim De Meyer, Veerle Melotte
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2023-08-01
Collection:	Epigenetics & Chromatin
Sujets:	DNA hypermethylation Pan cancer Neural differentiation REST
Accès en ligne:	https://doi.org/10.1186/s13072-023-00505-7
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