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TiRank prioritizes phenotypic niches in tumor microenvironment for clinical biomarker discovery

Abstract Background Tumor microenvironment (TME) plays a crucial role in cancer progression, metastasis, and treatment response. Recent advances in single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have provided valuable insights into the cellular diversity and spatial organiza...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Yuxiang Lin, Zening Huang, Ziyan Lin, Yating Lin, Jinsheng Song, Ling Luo, Jiayao Chi, Yeyang Zheng, Youxin Gao, Junjie Lin, Xinyu Li, Chenyu Liang, Lei Zhang, Xinkang Wang, Yuqin Sun, Rongshan Yu, Qiyue Chen, Mengsha Tong
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-02-01
Rangatū:Genome Medicine
Ngā marau:
Spatial transcriptomics
Tumor microenvironment
Clinically relevant spatial niches
Gastric cancer
Neo-adjuvant chemoimmunotherapy response
Urunga tuihono:https://doi.org/10.1186/s13073-026-01604-2
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