Protective effects of naringin against oxaliplatin-induced testicular damage in rats: Involvement of oxidative stress, inflammation, endoplasmic reticulum stress, apoptosis, and histopathology

Objective(s): Oxaliplatin (OXL) is a platinum-based chemotherapeutic agent widely used in the treatment of colorectal cancer. Unfortunately, this important drug also causes unwanted side effects such as neuropathy, ototoxicity, and testicular toxicity. This study aimed to investigate the possible pr...

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Bibliografische Detailangaben

Hauptverfasser:	Nurhan Akaras, Cihan Gur, Cuneyt Caglayan, Fatih Kandemir
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Mashhad University of Medical Sciences 2024-04-01
Schriftenreihe:	Iranian Journal of Basic Medical Sciences
Schlagworte:	apoptosis endoplasmic reticulum - stress inflammation naringin oxaliplatin testicular toxicity
Online-Zugang:	https://ijbms.mums.ac.ir/article_23650_0949440f794564318f09c6c1326145b2.pdf
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