CD4+FOXP3+ Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation

Since their discovery CD4+FOXP3+ regulatory T cells (Tregs) represented a promising tool to induce tolerance in allogeneic hematopoietic cell transplantation. Preclinical models proved that adoptive transfer of Tregs or the use of compounds that can favor their function in vivo are effective for pre...

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Detalhes bibliográficos

Principais autores:	Antonella Mancusi, Sara Piccinelli, Andrea Velardi, Antonio Pierini
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-12-01
coleção:	Frontiers in Immunology
Assuntos:	regulatory T cells allogeneic hematopoietic transplantation tolerance engraftment graft-vs.-host-disease graft-vs.-tumor effect
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fimmu.2019.02901/full
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