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Efficacy and safety of estradiol/dydrogesterone combined with escitalopram in the treatment of anxiety and depression in perimenopausal women: a randomized controlled trial

BackgroundTo investigate the efficacy and underlying mechanisms of a combined therapy of estradiol/dydrogesterone and escitalopram in treating perimenopausal anxiety and depression.MethodsA total of 195 patients were randomized to receive escitalopram, estradiol/dydrogesterone, or combination therap...

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Bibliografiske detaljer
Principais autores: Shufang Wu, Guiying Zeng, Saisai Chen, Hongbin Chen, Senpei Xie, Jiabao Zhang, Yingchun Xiao, Nan Liu, Hui Chen, Ronghua Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Physiology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphys.2026.1728736/full
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