Chemoresistance Transmission via Exosome-Transferred MMP14 in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies. Gemcitabine is the most commonly used chemotherapy for the treatment of PDAC, but the development of drug resistance still remains challenging. Recently, exosomes have emerged as important mediators for intercellular commu...

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Autors principals:	Xinyuan Li, Kai Li, Mengmeng Li, Xiaoyu Lin, Yu Mei, Xuemei Huang, Huanjie Yang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-02-01
Col·lecció:	Frontiers in Oncology
Matèries:	MMP14 exosome gemcitabine resistance CD44 pancreatic cancer
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2022.844648/full
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