Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity
Huntington’s disease (HD) is caused by a CAG-repeat expansion mutation in the Huntingtin (HTT) gene. It is characterized by progressive psychiatric and neurological symptoms in combination with a progressive movement disorder. Despite the ubiquitous expression of HTT, pathological changes occur quit...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI AG
2021-07-01
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| Серии: | Toxins |
| Предметы: | |
| Online-ссылка: | https://www.mdpi.com/2072-6651/13/7/487 |
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