Praliciguat alleviates ferroptosis and inflammation in renal ischemia/reperfusion injury by targeting the AMPK/ACC/PUFA pathway

Objective: To investigate the reno-protective effects of praliciguat in a rat model of renal ischemia/reperfusion injury (IRI), focusing on its modulation of the AMPK/ACC/PUFA pathway, ferroptosis, and inflammation. Methods: Twenty-four male Sprague-Dawley rats were randomly assigned to four grou...

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Principais autores:	Nisreen Abd Alhassan Hamza Alshimary, Thu-Alfeqar Razzaq Tweij
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Babcock Medical Society 2025-12-01
סדרה:	Babcock University Medical Journal
נושאים:	AMPK/ACC/PUFA Pathway Ferroptosis Praliciguat Nephroprotection Renal Ischemia/Reperfusion Injury
גישה מקוונת:	https://bumj.babcock.edu.ng/index.php/bumj/article/view/992
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