Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response

Abstract Humoral immune-related adverse events, including hypogammaglobulinemia and B cell depletion, pose long-term infection risks after chimeric antigen receptor T cell therapy (CARTx) for hematologic malignancies. This prospective study evaluates the kinetics of pathogen-specific humoral immunit...

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Egile Nagusiak:	Stosh Ozog, Elizabeth M. Krantz, Karyn Tindbaek, Julian Munoz, Winnie L. Liu, Clementine Chalal, Sara Pernikoff, Khaleel Yahya, Terry Stevens-Ayers, Sayan Dasgupta, Andrew J. Cowan, Damian J. Green, Jordan Gauthier, Brian G. Till, Rebecca A. Gardner, Mazyar Shadman, Marie Bleakley, Michael Boeckh, Jim Boonyaratanakornkit, Cameron J. Turtle, Joshua A. Hill
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2026-04-01
Saila:	Nature Communications
Sarrera elektronikoa:	https://doi.org/10.1038/s41467-026-71473-1
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