Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver

C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, little is known about the molecular mechanisms that control pig CRP gene expression. The main g...

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Autors principals:	Carles Hernández-Banqué, Teodor Jové-Juncà, Daniel Crespo-Piazuelo, Olga González-Rodríguez, Yuliaxis Ramayo-Caldas, Anna Esteve-Codina, Marie-José Mercat, Marco C. A. M. Bink, Raquel Quintanilla, Maria Ballester
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-09-01
Col·lecció:	Frontiers in Immunology
Matèries:	C-reactive protein fine-mapping luciferase assays enhancer pig RNA-seq
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250942/full
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