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Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion.

Mucins are heavily glycosylated proteins that give mucus its gel-like properties. Moreover, the glycans decorating the mucin protein core can alter the protective properties of the mucus barrier. To investigate whether these alterations could be parasite-induced we utilized the Trichuris muris (T. m...

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Bibliografiske detaljer
Principais autores: Sumaira Z Hasnain, Paul A Dawson, Rohan Lourie, Peter Hutson, Hui Tong, Richard K Grencis, Michael A McGuckin, David J Thornton
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2017-02-01
Serier:PLoS Pathogens
Online adgang:http://europepmc.org/articles/PMC5325613?pdf=render
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