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Targeting ferroptosis in cancer: from mechanistic insights to therapeutic approaches

Abstract Ferroptosis is a promising programmed cell death modality for cancer therapy, driven by iron overload and the accumulation of phospholipid peroxides that culminate in lethal membrane damage. Over the past decade, emerging evidence supports the concept that ferroptosis can be harnessed as an...

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Principais autores: Junqi Wang, Dawei Guo, Shanxiang Jiang, Wenda Wu, Xiuge Gao
Format: Artigo
Jezik:Inglês
Izdano: Springer 2026-03-01
Serija:Molecular Biomedicine
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Online dostop:https://doi.org/10.1186/s43556-026-00416-5
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