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Cohesin reconstitution and homologous recombination repair of DNA double-strand breaks in late mitosis

The cohesin complex maintains sister chromatid cohesion from S phase to anaphase onset. Cohesin also plays roles in chromosome structure and DNA repair. In yeast, the cohesin subunit Scc1 is cleaved at anaphase onset to allow segregation in an orderly manner, although some residual cohesin subunits...

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Principais autores: Jessel Ayra Plasencia, Sara Medina-Suárez, Esperanza Hernández-Carralero, Jonay García-Luis, Lorraine S Symington, Félix Machín
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2025-11-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/92706
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