IgM Hyposialylation Modulates Podocyte Vulnerability in Patients With Idiopathic Nephrotic Syndrome

Introduction: Altered Ig glycosylation has been implicated in antibody-mediated podocytopathies; however, the functional relevance of IgM sialylation remains poorly defined. Previous evidence suggests that circulating cationic or hyposialylated IgM may contribute to podocyte vulnerability in idiopat...

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Hlavní autoři:	Sonia Spinelli, Sofia Gaudiano, Andrea Garbarino, Francesca Lugani, Edoardo La Porta, Andrea Petretto, Martina Bartolucci, Chiara Lavarello, Nicole Grinovero, Ilaria Musante, Paolo Scudieri, Antonella Trivelli, Giorgio Piaggio, Alberto Magnasco, Maria Ludovica Degl’Innocenti, Simona Granata, Gianluigi Zaza, Enrico Verrina, Giovanni Candiano, Maurizio Bruschi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-08-01
Edice:	Kidney International Reports
Témata:	hyposialylation IgM glycosylation podocytopathies podocyte injury sialidase
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2468024926028305
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