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Eculizumab for paroxysmal nocturnal haemoglobinuria: catastrophic health expenditure in Nepalese patients

Abstract Paroxysmal nocturnal hemoglobinuria (PNH) results from a mutation in the phosphatidylinositol glycan class-A gene which causes uncontrolled complement activation with resultant intravascular hemolysis and its sequelae. Eculizumab is a terminal complement inhibitor that blocks this complemen...

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主要な著者: Sugat Adhikari, Surendra Sapkota, Suraj Shrestha, Kshitiz Karki, Anjan Shrestha
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2023-06-01
シリーズ:Orphanet Journal of Rare Diseases
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オンライン・アクセス:https://doi.org/10.1186/s13023-023-02779-2
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