Structure of a DNA G-Quadruplex Related to Osteoporosis with a G-A Bulge Forming a <i>Pseudo-loop</i>
Bone remodeling is a fine-tuned process principally regulated by a cascade triggered by interaction of receptor activator of NF-κB (RANK) and RANK ligand (RANKL). Excessive activity of the <i>RANKL</i> gene leads to increased bone resorption and can influence the incidence of osteoporosis. Although...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
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MDPI AG
2020-10-01
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| Serier: | Molecules |
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| Online adgang: | https://www.mdpi.com/1420-3049/25/20/4867 |
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