CSFV restricts necroptosis to sustain infection by inducing autophagy/mitophagy-targeted degradation of RIPK3

ABSTRACT As an essential component of host defense against infection, necroptosis is a novel highly regulated mode of cell death that is mediated by signaling complexes containing receptor-interacting protein kinase 1 (RIPK1) and RIPK3. Lymphocyte depletion and immunosuppression are typical clinical...

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Detalles Bibliográficos

Principais autores:	Keke Wu, Bingke Li, Xiaoai Zhang, Yiqi Fang, Sen Zeng, Wenshuo Hu, Xiaodi Liu, Xueyi Liu, Zhimin Lu, Xiaowen Li, Wenxian Chen, Yuwei Qin, Bolun Zhou, Linke Zou, Feifan Zhao, Lin Yi, Mingqiu Zhao, Shuangqi Fan, Jinding Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2024-01-01
Series:	Microbiology Spectrum
Assuntos:	autophagy necroptosis CSFV NS4A TRIM25 mitophagy
Acceso en liña:	https://journals.asm.org/doi/10.1128/spectrum.02758-23
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