Impacts of activation of the mitogen-activated protein kinase pathway in pancreatic cancer
Pancreatic cancer is characterized by constitutive activation of the mitogen-activated protein kinase (MAPK) pathway. Mutations of KRAS or BRAF and epigenetic abrogation of DUSP6 contribute synergistically to the constitutive activation of MAPK. Active MAPK induces the expression of a variety of gen...
Wedi'i Gadw mewn:
| Prif Awdur: | |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2015-02-01
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| Cyfres: | Frontiers in Oncology |
| Pynciau: | |
| Mynediad Ar-lein: | http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00023/full |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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