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Impacts of activation of the mitogen-activated protein kinase pathway in pancreatic cancer

Pancreatic cancer is characterized by constitutive activation of the mitogen-activated protein kinase (MAPK) pathway. Mutations of KRAS or BRAF and epigenetic abrogation of DUSP6 contribute synergistically to the constitutive activation of MAPK. Active MAPK induces the expression of a variety of gen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Toru eFurukawa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015-02-01
Cyfres:Frontiers in Oncology
Pynciau:
Mynediad Ar-lein:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00023/full
Tagiau: Ychwanegu Tag
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