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Evidence-based severity assessment of the forced swim test in the rat.

The forced swim test (FST) is a traditional assay, which has been used for more than 40 years to assess antidepressant effects of novel drug candidates. In recent years, a debate about the test has focused on the assumption that the FST is highly aversive and burdening for the animals because of the...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Laura Becker, Anne S Mallien, Natascha Pfeiffer, Christiane Brandwein, Steven R Talbot, André Bleich, Rupert Palme, Heidrun Potschka, Peter Gass
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2023-01-01
Rangatū:PLoS ONE
Urunga tuihono:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0292816&type=printable
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