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Low thalamic activity during a digit-symbol substitution task is associated with symptoms of subjective cognitive decline

IntroductionSubjective cognitive decline (SCD) may represent the earliest preclinical stage of Alzheimer's Disease (AD) for some older adults. However, the underlying neurobiology of SCD is not completely understood. Since executive function may be affected earlier than memory function in the progre...

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Principais autores: Akiko Mizuno, Helmet Talib Karim, Maria J. Ly, Brian J. Lopresti, Ann D. Cohen, Areej A. Ali, Chester A. Mathis, William E. Klunk, Howard J. Aizenstein, Beth E. Snitz
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-09-01
Serier:Frontiers in Psychiatry
Fag:
subjective cognitive decline
fMRI
digit-symbol substitution task
executive function
amyloid
Online adgang:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1242822/full
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