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Design, synthesis and biological evaluation of 2,5-diaryloxazolo[4,5-d]pyrimidin-7-ylamines as selective cytotoxic agents against HeLa cells

Nine novel functionalized 2,5-diaryloxazolo[4,5-d]pyrimidin-7-ylamines were designed, synthesized and characterized using 1H, 13C NMR, IR spectroscopy, elemental analysis, and liquid chromatography–mass spectrometry. Their anticancer activity was assessed against human cancer cell as well as non-can...

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Tallennettuna:
Päätekijät: Maryna V. Kachaeva, Agnieszka B. Olejniczak, Marta Denel-Bobrowska, Victor V. Zhirnov, Yevheniia S. Velihina, Stepan G. Pilyo, Volodymyr S. Brovarets
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Beilstein-Institut 2026-03-01
Sarja:Beilstein Journal of Organic Chemistry
Aiheet:
admet analysis
anticancer activity
2,5-diaryloxazolo[4,5-d]pyrimidin-7-ylamines
Linkit:https://doi.org/10.3762/bjoc.22.27
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