Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement
Griscelli syndrome type 2 (GS-2) is an inborn error of immunity characterized by partial albinism and episodes of hemophagocytic lymphohistiocytosis (HLH). It is caused by RAB27A mutations that encode RAB27A, a member of the Rab GTPase family. RAB27A is expressed in many tissues and regulates vesicu...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2020-12-01
|
| Seria: | Frontiers in Immunology |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.frontiersin.org/articles/10.3389/fimmu.2020.612977/full |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|