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Dopaminergic stimulation leads B-cell infiltration into the central nervous system upon autoimmunity

Abstract Background Recent evidence has shown dopamine as a major regulator of inflammation. Accordingly, dopaminergic regulation of immune cells plays an important role in the physiopathology of inflammatory disorders. Multiple sclerosis (MS) is an inflammatory disease involving a CD4+ T-cell-drive...

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Principais autores: Carolina Prado, Francisco Osorio-Barrios, Paulina Falcón, Alexandra Espinoza, Juan José Saez, María Isabel Yuseff, Rodrigo Pacheco
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-12-01
coleção:Journal of Neuroinflammation
Assuntos:
Regulatory B lymphocytes
Antigen-presenting cells
Chemokine receptors
Neuroinflammation
Experimental autoimmune encephalomyelitis
Central nervous system homing
Acesso em linha:https://doi.org/10.1186/s12974-021-02338-1
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