Toxicity of ubiquitous tire rubber antiozonant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its transformation product 6PPD-quinone (6PPD-Q) in primary human hepatocytes and liver spheroids

The tire rubber antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPD-Q) were recently found in human bodies. Though 6PPD/6PPD-Q showed species-dependent toxicity in animals, human relevant data are scarce. Here, primary human hepatocytes...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Daniel J. Yeisley, Lijun Ren, Katy S. Papineau, Laura K. Schnackenberg, Gonçalo Gamboa da Costa, Tucker A. Patterson, Suzanne C. Fitzpatrick, Qiang Shi
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-09-01
سلاسل:	Biochemistry and Biophysics Reports
الموضوعات:	6PPD 6PPD-Q Primary human hepatocytes Liver injury Spheroids
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2405580825002869
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!