A glyco-engineering approach for site-specific conjugation to Fab glycans
Effective processes for synthesizing antibody-drug conjugates (ADCs) require: 1) site-specific incorporation of the payload to avoid interference with binding to the target epitope, 2) optimal drug/antibody ratio to achieve sufficient potency while avoiding aggregation or solubility problems, and 3)...
שמור ב:
| Principais autores: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis Group
2023-12-01
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| סדרה: | mAbs |
| נושאים: | |
| גישה מקוונת: | https://www.tandfonline.com/doi/10.1080/19420862.2022.2149057 |
| תגים: |
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