Tauopathy strains differentially replicate in vitro in the presence of mutant tau monomer

Tauopathies are a group of neurodegenerative diseases caused by misfolding of the protein tau into a β-sheet rich conformation. By inducing misfolding of additional tau monomers, these pathogenic fibrils replicate and spread progressive disease throughout the brain. While frontotemporal lobar degene...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Christine K. Brown, Matthew P. Frost, Sara A.M. Holec, William W. Seeley, Lea T. Grinberg, Steven H. Olson, Amanda L. Woerman
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2025-10-01
Σειρά:	Neurobiology of Disease
Θέματα:	Argyrophilic grain disease Corticobasal degeneration Frontotemporal lobar degenerative diseases Glial globular tauopathy Progressive supranuclear palsy Tau strains
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S0969996125002682
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